RAF Typhoon FGR4s have operated alongside French aircraft in a coordinated attack against an underground arms cache in Syrian territory operated by the IS group, according to the UK's MoD.
The location, identified by surveillance, was assessed as housing weapons and explosive materials, the announcement noted, and was situated in mountains just north of Palmyra in Syria's central region.
"Our aircraft employed precision-guided Paveway IV munitions to hit a several approach shafts down to the facility... preliminary assessments indicate the target was engaged successfully," the MoD said.
There was no evidence of any civilian impact in the attack on Saturday evening and each participating jet returned to base without incident, the ministry further stated.
The Typhoon FGR4s were backed up by a Voyager aerial refuelling aircraft.
IS - also known as ISIS - enforced militant control over large swathes of both Syria and Iraq before its territorial defeat in 2019.
"This operation underscores our UK leadership, and resolve to operate in unison with our allies, to eliminate any resurgence of the terrorist group and their harmful and extremist ideologies in the area," Britain's Defence Chief John Healey stated.
British military aircraft have conducted surveillance missions over Syrian airspace to "prevent any attempted comeback" of Islamic State subsequent to its routing at the climactic battle in Baghuz in the year 2019, the MoD reported.
"I want to thank all the members of our armed forces participating in this strike for their expertise and their courage," he said. "They were part of a great many British troops stationed over the festive period. This operation, to take out terrorist threats who threaten our security, shows how British military are ready to step up, throughout the year, keeping Britain secure domestically and powerful internationally."
During December, the American forces carried out what it termed a "large-scale strike" against Daesh sites in the country, after an attack resulted in the deaths of two US servicemembers and a civilian interpreter in the Palmyra area.
The United Nations says Daesh still maintains roughly 5-7 thousand fighters in Syria and Iraq.
